Fibroblast cells. Confocal light micrograph of fibroblast cells. The cell nuclei, which contain the cells' genetic information, are blue. The protein filaments that make up the cytoskeleton are orange. The cytoskeleton maintains the cells' shape, allow some cellular mobility and are involved in intracellular transport. Fibroblasts are cells that give rise to connective tissue such as collagen, the main structural protein in the body. They are important in wound healing.