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Transcription regulator molecule. Molecular model of the transcription regulator negative cofactor 2 complexed with the TATA box-binding protein (TBP) and DNA (deoxyribonucleic acid). TBP is a general transcription factor that binds specifically to the TATA box DNA sequence during DNA transcription. TATA boxes are found in the promoter region of a gene, the area where transcription is initiated from.

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