Neurological effects of diabetes drugs. Conceptual image of a human brain enclosed in a hollow icosahedron with its edges consisting of various drugs used to treat the effects of diabetes. This represents the neurological side-effects of the drugs. The drugs include metformin, sulphonylureas, rosiglitazone, and DPP-4 inhibitors. Side effects for some antidiabetic drugs can include a higher risk of strokes. Diabetes is a condition where the body is resistant to or fails to produce the insulin needed to break down sugars in the blood. Insulin or drugs can be used to lower the blood sugar to normal levels.