A portrait of Queen Victoria (1819-1901) and some of her descendants. Victoria was Queen of England from 1837 to 1901. Inbreeding was common among royal families, causing genetic disorders. Victoria was married to her first cousin. She was a carrier of the gene causing hemophilia (recurrent bleeding). Her son, Prince Leopold, died of this. Two of Victoria's daughters were carriers of the gene, passing the disease on to the Spanish and Russian royal families.