The Schick test, invented between 1910 and 1911 was a test used to determine whether or not a person was susceptible to diphtheria. It was named after its inventor, B矇la Schick a Hungarian-American pediatrician. The test was a simple procedure. A small amount of diluted diphtheria toxin is injected intradermally into the arm of the person. If the person does not have enough antibodies to fight it off, the skin around the injection will become red and swollen, indicating a positive result. This swelling disappears after a few days. If the person has an immunity, then little or no swelling and redness will occur, indicating a negative result. The test was created when immunizing agents were scarce and not very safe, however as newer and safer toxoids were made available there was no more requirement for susceptibility tests.

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