Charles Herbert Best (February 27, 1899 - March 31, 1978) was an American-Canadian medical scientist who worked as an assistant to Frederick Banting and played a major role in the discovery of the pancreatic hormone insulin thus enabling an effective treatment for diabetes. However, when the Nobel Prize Committee honored Banting and J.J.R. Macleod with the 1923 Nobel Prize in Medicine for the discovery of insulin, they ignored Charles Best. This angered Banting who then chose to share half of the prize money with Best. In his later years, he was an adviser to the Medical Research Committee of the United Nations World Health Organization. He received 18 Honorary Degrees from Universities around the World. He died in 1978 at the age of 79.