Micrograph depicts the histopathological changes found in the case of Kaposi's sarcoma lesions. This skin biopsy of what turned out to be a Kaposi's sarcoma lesion at a high magnification depicts two characteristic findings found in such lesions, which includes remnants of extravasated erythrocytes (RBCs), and deposits of hemosiderin. Kaposi's sarcoma (KS) is a tumor caused by Human herpesvirus 8 (HHV8), also known as Kaposi's sarcoma-associated herpesvirus (KSHV). It became more widely known as one of the AIDS defining illnesses in the 1980s. The viral cause for this cancer was discovered in 1994. Kaposi's sarcoma (KS) is a systemic disease that can present with cutaneous lesions with or without internal involvement.