The Great Lozenge-Maker - a hint to paterfamilias. Cartoon by John Leech in Punch alluding to the Bradford Sweet Poisonings of 1858, as represented by a skeleton of death mixing sweets made with plaster of paris and arsenic. The 1858 Bradford sweets poisoning was the arsenic poisoning of more than 200 people in Bradford, England, when sweets accidentally made with arsenic were sold from a market stall. Twenty-one victims died as a result. The event contributed to the passage of the Pharmacy Act 1868 in the United Kingdom and legislation regulating the adulteration of foodstuffs