Depression. Conceptual artwork of a barren landscape surrounding the face of a person (brain shown), representing depression or schizophrenia, with the brighter landscape inside his head representing treatment of the disorder. A person suffering from depression experiences feelings of sadness and hopelessness. As a result they may become withdrawn and lose interest in events occurring around them. This image may also represent schizophrenia, a mental disorder which causes the sufferer's perception of the outside world to become altered from reality. Schizophrenia can cause depression.