Colorectal cancer and its treatments. At the top right the colon in view of radiological type from or zoom a colon seen in section with 2 cancerous tumors at 2 different stages highlighting the vascularization of the tumor. In the window at the bottom left, zoom on one of the blood capillaries of the tumor with details of the transcriptional replication process thanks to VEGF (blue beads), a vascular growth factor produced by the tumor, which will bind to the VEGF receptor ( blue) present in the vessel wall. The tumor cell also produces EGF growth factors (yellow beads) which, by binding to the EGF receptor (yellow) of the tumor cell, causes a cascade of signaling responsible for cell proliferation and resistance to apoptosis.