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These hematopoietic stem cells give two lines: a myeloid line that differentiates into red blood cells, platelets, monocytes and polymorphonuclear cells and a lymphoid line which differentiates into T lymphocytes, B lymphocytes. In this drawing, it is indicated which immune cells are affected during chronic lymphoid leukemia: hematopoietic stem cells and the lymphoid line, including B lymphocytes

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