Acne around the hair follicle, sebaceous hypersecretion, hyperkeratinization, proliferation. Skin section of the epidermis and dermis. Normal hair follicle on the right and acne pimple in the center. The acne pimple is formed around the hair follicle with sebum retention, hyperkeratinization and inflammation of the epidermis caused by glycerides (in yellow) under the action of the bacteria Propionibacterium acnes (in red). The sebaceous gland is in hypersecretion. Proteolytic enzymes cause rupture and bacterial growth in the dermis. Polynuclear cells from blood vessels are flowing.