Colorectal cancer and its treatments. Above right, the colon in radiological type from where a zoom of a colon seen in section with 2 cancerous tumors at 2 different stages highlighting the vascularization of the tumor. In the window at the bottom left, zoom in on one of the blood capillaries of the tumor with details of the transcription replication process thanks to VEGF (blue beads), a vascular growth factor produced by the tumor, which will bind to the VEGF receptor ( blue) present in the vessel wall. The tumor cell also produces the growth factors EGF (yellow beads) which, by binding to the EGF receptor (yellow) of the tumor cell, causes a cascade of signals responsible for cell proliferation and resistance to apoptosis.