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Cysteine protease active site of the SARS-CoV-2 main protease, molecular model. The active site of the SARS-CoV-2 main protease is a catalytic dyad of cysteine and histidine side chains, shown here in ball-and-stick style. This cysteine protease motif is common in biochemistry. Atoms are colour-coded: carbon is black, hydrogen is white, nitrogen is blue, and sulphur is yellow.

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