Light micrograph of Candida albicans fungus (white, ovals, centre) in a liver tissue specimen from a male patient with systemic candidiasis. The fungus is undergoing budding, a form of asexual reproduction. Candidiasis is an infection caused by the single-celled fungus (yeast) Candida. Patients who are hospitalised or have a weakened immune system are at greater risk of developing systemic candidiasis. Systemic candidiasis occurs when the fungus enters the bloodstream (candidaemia) and spreads to one or more organs. If left untreated candidaemia can lead to death. Treatments include a range of antifungal medications.