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Apo structure of human mTORC2 complex, molecular model. mTORC2 (mTOR Complex 2) is an acutely rapamycin-insensitive protein complex formed by serine/threonine kinase mTOR that regulates cell proliferation and survival, cell migration and cytoskeletal remodelling. Shown are the serine/threonine-protein kinase mTOR (blue), the target of rapamycin complex subunit LST8 (yellow), the rapamycin-insensitive companion of mTOR (purple) and the target of rapamycin complex 2 subunit MAPKAP1 (green).

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