Sir Christopher Wren PRS (30 October 1632 ? 8 March 1723) is one of the most highly acclaimed English architects in history. He was accorded responsibility for rebuilding 52 churches in the City of London after the Great Fire in 1666; including what is regarded as his masterpiece; St. Pauls Cathedral; on Ludgate Hill; completed in 1710. Educated in Latin and Aristotelian physics at the University of Oxford; Wren was a notable anatomist; astronomer; geometer; and mathematician-physicist; as well as an architect. He was a founder of the Royal Society (president 1680?82); and his scientific work was highly regarded by Isaac Newton and Blaise Pascal.