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Illustration of tirzepatide (silver helix) bound to a glucagon-like peptide-1 (GLP-1) transmembrane receptor (multi-coloured helices across membrane). A G protein (3d multicoloured structure), part of the GLP-1 signalling cascade, is visible below the membrane. Tirzepatide is a drug used to treat type 2 diabetes and obesity. It functions as a glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) agonist (mimic), which are natural hormones secreted in the gastrointestinal tract when we eat. They work by binding to GLP-1 and GIP receptors throughout the body and stimulating insulin secretion, inhibiting glucagon secretion, and slowing down gastric emptying. These effects all lower blood sugar levels, making tirzepatide a treatment option for type 2 diabetes.

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達志影像

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3 dimensional 3d 7 helix receptor action analogue antidiabetic artwork binding biochemical biochemistry biological biology blood sugar control bound cell membrane cgi diabetes diabetes medication diabetes treatment digitally generated drug endocrine system endocrinological endocrinology g protein gip gip receptor glp glp-1 glp-1 agonist glucagon like peptide glucagon-like peptide-1 glucose-dependent insulinotropic polypeptide glucose-dependent insulinotropic polypeptide receptor glycaemic control glycemic control gs protein healthcare hormone illustration ly3298176 mechanism of action medical medication medicine membrane molecular structure no-one nobody peptides pharma pharmaceutical pharmaceuticals pharmacological pharmacology phospholipid bilayer plasma membrane proteins receptor ribbon diagram signalling cascade structure three dimensional tirzepatide transmembrane transmembrane receptor type 2 diabetes weight loss yellow background

2 3 3d 7 action action agonist analogue antidiabetic artwork background bilayer binding biochemical biochemistry biological biology blood bound cascade cell cgi control control control diabetes diabetes diabetes diabetes diagram digitally dimensional dimensional drug endocrine endocrinological endocrinology g generated gip gip glp glp-1 glp-1 glucagon glucagon-like glucose-dependent glucose-dependent glycaemic glycemic gs healthcare helix hormone illustration insulinotropic insulinotropic like loss ly3298176 mechanism medical medication medication medicine membrane membrane membrane molecular no-one nobody of peptide peptide-1 peptides pharma pharmaceutical pharmaceuticals pharmacological pharmacology phospholipid plasma polypeptide polypeptide protein protein proteins receptor receptor receptor receptor receptor ribbon signalling structure structure sugar system three tirzepatide transmembrane transmembrane treatment type weight yellow

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