'Khosrow and Shirin', also spelled Khosrau and Shirin, Chosroes and Shirin, Husraw and Shireen and Khosru and Shirin, is the title of a celebrated Persian tragic romance by the Persian poet Nizami Ganjavi (1141??209) who also wrote 'Layla and Majnun'.

It tells an elaborate fictional version of the story of the love of the Sasanian king Khosrow II for the Armenian princess Shirin, who becomes his queen. The narrative is a love story of Persian origin which is also well-known from the great historical poem the Shahnameh.