Flavia Domitilla Major (1st century CE), also known as Domitilla the Elder, was the first wife of Vespasian. She was the daughter of Flavius Liberalis, a humble quaestor's clerk, and was a formal mistress to an African knight before her marriage to Vespasian. She married Vespasian some time around 38 CE, and was the mother of future emperors Titus and Domitian, as well as Domitilla the Younger, and grandmother of Saint Flavia Domitilla. She died before Vespasian became emperor, some time around 65 CE.