Illustration of the MTAP (S-methyl-5'-thioadenosine phosphorylase, blue) enzyme binding to a substrate (red). MTAP enzyme catalyses the phosphorolysis of 5'-methylthioadenosine to S-adenosylmethionine. The gene encoding for MTAP is often deleted in human cancers because it is co-deleted with the tumour suppressor gene p16 adjacent to it.

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達志影像

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