Illustration of engineered receptors (light blue) on the surface of a T-lymphocyte bind specifically to CD19-antigen molecules (red) on a leukemia cell. This activates a signal cascade in the T-cell leading to the segregation of vesicles that contain perforin and granzyme. The perforins build channels for the granzymes which enter the leukemia cell and activate finally the apoptosis (cell death) of the cancer cell.
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Details
Creative#:
TPG33507779
Source:
達志影像
Authorization Type:
RF
Release Information:
須由TPG 完整授權
Model Release:
N/A
Property Release:
N/A
Right to Privacy:
No
Same folder images:
chimericantigenreceptorchimericimmunoreceptorchimerict-cellreceptorartificialt-cellreceptormembranereceptorbiomoleculecd-19antigent-cellcartherapycancerleukemiat-celltherapybioengineeringcellmembranesignalproteinimmunesystemproteinneuroblastomacellperforingranzymeapoptosisimmunotherapytumorspecificcytokineantibodyenzymecelldeathbiotechnologymolecularbiologybiochemicalbiochemistryartworkbiological
antibodyantigenantigenapoptosisartificialartworkbiochemicalbiochemistrybioengineeringbiologicalbiologybiomoleculebiotechnologycancercarcd-19cellcellcellchimericchimericchimericcytokinedeathenzymegranzymeimmuneimmunoreceptorimmunotherapyleukemiamembranemembranemolecularneuroblastomaperforinproteinproteinreceptorreceptorreceptorreceptorsignalspecificsystemt-cellt-cellt-cellt-celltherapytherapytumor