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Illustration of human ARTD2/PARP2 (poly(ADP-ribosyl)transferase-like 2) complexed with DNA (deoxyribonucleic acid, helical). ARTD2/PARP2 belongs to a family of enzymes known as ADP-ribosyltransferases. It is activated in response to DNA damage and adds poly-ADP-ribose units to the DNA, which triggers the recruitment of DNA repair machinery.

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